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Re: 15 Years Plus Club - Survivors with Stage IV ASPS over 15yrs
Posted: Mon Apr 12, 2010 6:31 pm
by Ivan
I am half way to making that list
Re: 15 Years Plus Club - Stage IV ASPS survivors over 15 yea
Posted: Tue Aug 16, 2011 9:28 am
by Feng zhou
J BUON. 2011 Apr-Jun;16(2):376-7.
Long term survival in a metastatic alveolar soft part sarcoma at the time of diagnosis: a case with 17 years of follow-up.
Kos FT, Uncu D, Oksuzoglu B, Aksoy S, Ozdemir N, Odabas H, Isik M, Civelek B, Zengin N.
PMID: 21766518 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/21766518
Re: 15 Years Plus Club - Stage IV ASPS survivors over 15 yea
Posted: Sat Aug 20, 2011 3:09 pm
by Amanda
Feng :0
Thank you so much for posting this!
Feng zhou wrote:J BUON. 2011 Apr-Jun;16(2):376-7.
Long term survival in a metastatic alveolar soft part sarcoma at the time of diagnosis: a case with 17 years of follow-up.
Kos FT, Uncu D, Oksuzoglu B, Aksoy S, Ozdemir N, Odabas H, Isik M, Civelek B, Zengin N.
PMID: 21766518 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/21766518
Re: 15 Years Plus Club - Stage IV ASPS survivors over 15 yea
Posted: Fri Dec 09, 2011 8:19 am
by Feng zhou
This is an article published in 2011 on the Detection of ASPL / TFE3 fusion transcripts. Reported on 18 ASPS patients, including 5 follow-up of more than 100 months survival, the longest 2 cases have been followed up 185 months.
http://www.springerlink.com/content/nx8 ... ltext.html
Re: 15 Years Plus Club - Stage IV ASPS survivors over 15 yea
Posted: Thu Apr 25, 2013 4:57 pm
by Bonni Hess
Dear Feng zhou,
Thank you for sharing this important and very detailed study. The data and results of the study confirm for me my anecdotal observations of the past ten+ years that seem to indicate that "Poor prognostic factors have been reported to include older patient age and larger tumour size and of course metastatic disease at presentation [2, 19]. In our series, the ten patients who are alive without evidence of disease were somewhat younger than the eight who died of disease or are alive with metastatic disease, and the former group had significantly smaller tumours (8/10 had tumours 5 cm or less compared to 8/8 having tumours of 7 cm or more)."
Of course there are exceptions to this, and a pro-active and very knowledgedable treatment approach is certainly a significant factor, although sadly it doesn't always change the ultimate outcome. The apparent relation between tumor size and survival also indicates to me the importance of removing the primary tumor and removing/destroying other mets at the smallest possible size after diagnosis.
With deepest gratitude for your sharing, and continued Hope,
Bonni