Cure Alveolar Soft Part Sarcoma International (iCureASPS)

What is hypervitaminosis A?

Hypervitaminosis A, or vitamin A toxicity, occurs when you have too much vitamin A in your body.

This condition may be acute or chronic. Acute toxicity occurs after consuming large amounts of vitamin A over a short period of time, typically within a few hours or days. Chronic toxicity occurs when large amounts of vitamin A build up in your body over a long period of time.

Symptoms include changes to vision, bone pain, and skin changes. Chronic toxicity can lead to liver damage and increased pressure on your brain.
https://www.healthline.com/health/hypervitaminosis-a

Causes of hypervitaminosis A

Excess amounts of vitamin A are stored in your liver, and it accumulates over time. Most people develop vitamin A toxicity by taking high-dose dietary supplements, possibly due to megavitamin therapy. A megavitamin therapy involves consuming very large doses of certain vitamins in an attempt to prevent or treat diseases.

It may also be caused by long-term use of certain acne treatments that contain high doses of vitamin A, such as isotretinoin (Sotret, Absorica).

Acute vitamin A toxicity is usually the result of accidental ingestion when it occurs in children.