Recommend. for the Management of hand-foot skin reaction

Questions about chemotherapy protocols, side effects, drugs interactions, use complimentary and alternative therapy during the treatment etc.

Recommend. for the Management of hand-foot skin reaction

Postby Olga » Mon Mar 22, 2010 8:52 am

Practical considerations in the management of hand-foot skin reaction caused by multikinase inhibitors
http://www.communityoncology.net/journa ... 701023.pdf

Multikinase inhibitors (MKIs, eg, sorafenib, sunitinib, cediranib etc) are oral anticancer agents associated with handfoot
skin reaction (HFSR), a cutaneous adverse event affecting 20%–40% of patients treated with these
drugs. Although usually mild, symptoms of HFSR can evolve into a painful condition, resulting in a shortened
duration or intensity of cancer treatment. An international, interdisciplinary panel of experts recently
provided the first consensus recommendations for the management of MKI-associated HFSR.
Olga
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