Limtations of the CT scan readings for the ASPS lung mets
Posted: Fri Jul 08, 2011 9:07 am
ASPS lung mets are often small and slow growing and there is a technical problem to analyze the small decrease or increase when it is found comparing between 2 consecutive scans:
Variability of Lung Tumor Measurements on Repeat Computed Tomography Scans Taken Within 15 Minutes
Gregory J. Riely, MD, PhD, Memorial Sloan-Kettering Cancer
http://jco.ascopubs.org/content/early/2 ... hort?rss=1
Conclusion:
Apparent changes in tumor diameter exceeding 1 to 2 mm are common on immediate reimaging. Increases and decreases less than 10% can be a result of the inherent variability of reimaging. Caution should be exercised in interpreting the significance of small changes in lesion size in the care of individual patients and in the interpretation of clinical trial results.
Variability of Lung Tumor Measurements on Repeat Computed Tomography Scans Taken Within 15 Minutes
Gregory J. Riely, MD, PhD, Memorial Sloan-Kettering Cancer
http://jco.ascopubs.org/content/early/2 ... hort?rss=1
Conclusion:
Apparent changes in tumor diameter exceeding 1 to 2 mm are common on immediate reimaging. Increases and decreases less than 10% can be a result of the inherent variability of reimaging. Caution should be exercised in interpreting the significance of small changes in lesion size in the care of individual patients and in the interpretation of clinical trial results.