Cure Alveolar Soft Part Sarcoma International (iCureASPS)

Metastasis Initiation Precedes Detection of Primary Cancer—Analysis of Metastasis Growth in vivo in a Colorectal Cancer Test Case Abstract Most cases of deaths from colorectal cancer (CRC) result from metastases, which are often still undetectable at disease detection time. Even so, in many cases, s...

Hello Cindy Are they thinking the plate is not allowing Sam’s jaw to heal properly? I bet you are right about the pains being a tumor reaction . Josh feels pains well before scans show inflammation and or reaction to his infusion meds , with his tumors .Especially in his chest area . However do have...

D.ap wrote: ↑Fri Jun 30, 2023 5:25 am Sarah
So glad that the VATS procedure is behind* you.
Let us know how you continue to improve and how the scans look .

Love ,

Sarah
Glad you are able to exercise!
Exercise really helps with our overall well being.

Does your onc require contrast with your MRI ?

Hello Johannes and Elisa

Nhi is also on the nivolimab/Yervoy combination.
She is also battling femur tumors .

Looking forward to hearing of results with the new treatment.

Much love ,

Sarah
So glad that the VATS procedure is begin you.
Let us know how you continue to improve and how the scans look .

Love ,

Hello Ivan ,

That’s really wonderful to hear !so incredibly happy to hear of .
Love ,

Hello again Nino Good advice to wait until your cold is better . I’d sure hope that a brain scan would be performed before you start axitinib as if the healing isn’t complete then there is more of a chance for bleeding from the tki ,as well as inflammation later from prembro. Certainly I’m not a doc...

Hello Nino,

Thank you for the update .
Will you start with axitinib, then introduce Keytruda weeks after ?
How are the brain tumors doing ?

Do let us know how you are doing.
Wishing you the best ❣️
Love,

Thanks for the update Nhi ..
Do you feel the lung study after SBRT , could apply to a response in your bone Mets after your scheduled treatment up and coming ?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505218/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505218/ Discussion Few studies have investigated tumor response predictors after SBRT. One of those, a recent study, revealed that the mean and maximum values of pre-SBRT standard uptake value could predict a complete response in lung metastases from var...

Osteoimmunology: Interactions of the Bone and Immune System Abstract Bone and the immune system are both complex tissues that respectively regulate the skeleton and the body’s response to invading pathogens. It has now become clear that these organ systems often interact in their function. This is p...

Hello Nhi , I’m truly glad to hear of your good stress happenings but sorry to hear of the tumor increases, which have offset the good stress to a degree . So your biggest increases are on your femur and on the base of the skull ? What kind of radiation will be administered to the femur and at what ...

The double edge sword of fibrosis in cancer Cancer-associated fibrosis is a critical component of the tumor microenvironment (TME) which significantly impacts cancer behavior. However, there is significant controversy regarding fibrosis as a predominantly tumor promoting or tumor suppressing factor....

Scar tissue drug dismantles cancer's defences to boost immunotherapy University of Southampton Immunotherapy has emerged as a powerful tool in the fight against cancer, but there are still many ways for the disease to elude its advances. One trick cancer cells use to evade an attack is to shield the...

Thanks, Debbie. The latest MRI was compared to an MRI from last year (we know that comparing CTs and MRIs would be difficult!). Johannes Certainly ☺️ The reason I ask if there was prior treatment and or treatments, to the femur is that in our experience those treatments can be exasperated by an ICI...