Cure Alveolar Soft Part Sarcoma International (iCureASPS)

Abstract Thyroid hormones take major part in normal growth, development and metabolism. Over a century of research has supported a relationship between thyroid hormones and the pathophysiology of various cancer types. In vitro studies as well as research in animal models demonstrated an effect of th...

https://www.rockefeller.edu/news/28096-first-evidence-inherited-genetics-can-drive-metastasis/#:~:text=Now%20researchers%20have%20shown%20for,existing%20genetics%20can%20promote%20metastasis. Sometimes cancer stays put, but often it metastasizes, spreading to new locations in the body. It has long b...

Dear Olga, Thanks for following up - what you say all makes sense. Trying to control the bone met (13cm long) with cryotherapy would seem difficult though, and radiation is not an option anymore. Elisa did start the Nivolumab + Ipilimumab combination and has received three rounds so far, which she ...

Ivan and family ,
Incredibly happy news !!
Sharing in your joy with you today and always .
Love ,
Debbie and family

Hi Sandra
How are you doing? Did you change back to the 12mg, Anlotinib?
When’s your next scan ?
Thinking of you today.☺️

Love,

Hello, Hope everyone is doing good.Just wanted to update on my treatment changes.So basically I had my MRI Brain and Bone scan in July and they came out clear.But the CT chest post VATS showed multiple nodules including some new tiny mets.So the VATS didn’t give the outcome we were expecting and sy...

Chemotherapies are the centerpiece of many cancer therapies. For patients, receiving chemotherapy is associated with great hopes, but also great physical and emotional strain. This is also because chemotherapy is not always as effective as it should be in every case of cancer. Chemosensitivity testi...

Hi Cindy !
Wow the reduction and disappearance of tumor masses , is incredibly good news !!

How big is the mass at this time ?

Thank you for the update and do let us know how Sam is doing .. especially after his surgery on the 20th of October.

Love ,

Hi Cindy , Josh has always used an oatmeal mixture of raisins & nuts for a boost to calories for weight gain , since 2015. So that definitely is a fiber usage . Is Sam’s weight disproportional to what he should be , for his height ? If that’s the case it maybe time to reduce his weight to help h...

Hello Sandra,
Are you still on a trial ?

Next Generation Sequencing Reveals Pathogenic and Actionable Genetic Alterations of Soft Tissue Sarcoma in Chinese Patients: A Single Center Experience Abstract Background: Next generation sequencing (NGS) has systematically investigated the genomic landscape of soft tissue sarcoma (STS) in Western ...

Thankfully, Sam is healing nicely from jaw surgery. His CT scans showed decrease in lung Mets, stable sternum and rib Mets,but the pesky knee tumor has caused a lot of destruction so he will need knee replacement surgery possibly next month. There is also a concerning area in his right hip which ma...

Discussion In this phase Ib/II trial, we found that the 6-month PFSR was 48% according to RECIST and independent central review. This outcome widely exceeds the 15% considered promising in the statistical assumption of this trial. This threshold was based on the European Organisation for Research an...

Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial Abstract Background Sarcomas exhibit low expression of factors related to immune response, which could explain the modest activity of PD-1 inhibitors. A potential strategy to convert a ...

Hey, Sam is healing nicely from having the plate removed from his jaw and had his 4th dose of Opdivo/yervoy. We are hoping the immunotherapy will work better by eliminating the chronic infection. He will have scans done 8-28 so hopefully I’ll report positive news! Also, he has slight case of thalas...